Abstract: Taking the teaching of cylindrical flow around Karman vortex street as an example, project-based learning (PBL) teaching method is adopted in the teaching of engineering fluid mechanics, and an advanced teaching mode of “problem + knowledge point” as the main line is proposed, which realizes the high-level and innovative challenges of the course. This paper expounds the application of problem-based teaching method. Through the combination of theory and practice, it builds a bridge between classroom and engineering practice, increases students’ learning input, and lets students experience the learning challenge of “jumping to get”.