Abstract: On the occasion of the 70 th anniversary of its establishment, this paper reviews the development of high-speed hydrodynamics research at the Institute of Mechanics, Chinese Academy of Sciences (IMECH). In its early years, guided by Qian Xuesen's Engineering Science, the institute established four strategic research domains: “aerospace, geomechanics, marine technology, and industrial and agricultural applications.” Qian Xuesen himself served as the director of the Hydrodynamics Laboratory. As institutional structures evolved, some research tasks were gradually transferred to specialized research institutes. In 1986, to support national marine development strategies, the Chinese Academy of Sciences founded the Marine Engineering Science and Technology Center, with Zheng Zhemin from IMECH appointed as its director, laying a solid foundation for ocean engineering technology development. The team on Transient Hydrodynamics of Bubbles and Cavitation, while practicing Qian Xuesen's Engineering Science, has consistently focused on identifying scientific research from engineering challenges and pursuing theoretical breakthroughs. Their work promotes deep integration of theoretical exploration, experimental validation, and engineering development, providing robust scientific and technological support for maritime endeavors.