Abstract: In order to explore the way to reform the course teaching by combining mechanics theory and innovative practice, this paper summarizes and investigates the teaching design and practice of the practical course “mechanics and practice”. This course is a practical course for students majoring in theoretical and applied mechanics at Shanghai University. It aims to bridge the gap between mechanics and practice for undergraduates. Students are trained to be able to use a combination of theoretical analysis, computational simulation and scientific experiments to investigate structural motion, vibration and other engineering problems related to their majors based on the basic knowledge of mechanics, and to communicate effectively. Teaching practice shows that the course “mechanics and practice” would strengthen the ability of students to think independently, apply their knowledge to solve problems and work in teams.