Abstract: During the new technology revolution around the world, China government is promoting the "new engineering" plan. Major of mechanics is one of the critical fundaments for engineering, which means that it requires more urgent improvements on the professional education and disciplinary construction in response to the revolution direction of engineering education in the new era. Based on biomechanics and biomimetics interdisciplinary course, this paper analyzed the main problems during the teaching of the interdisciplinary course (i.e., less knowledge of background for students, unclear teaching systematic content for teachers, and lack of attractive approach for teaching). Some specific attempts were then proposed and summarized for solving these problems, such as performing potential integrations with general education course for fresh students, basic mechanics course, and modern educational technology. We suggest that these teaching practices may offer potentially helpful reference and consulting for the development and improvement of interdisciplinary course in the existing engineering majors.