Abstract: In order to reveal the collision-induced fragmentation mechanism and laws of coarse particles during deep-sea mining hydraulic transport and optimize transport parameters, random geometric numerical reconstruction of coarse particles using a Python program was performed in this study, followed by full process simulation of particle collision-induced fragmentation. The validated numerical model was used to investigate the effects of particle impact velocity, impact angle, and particle size on fragmentation, and the typical fracture morphologies and mass loss rates was determined. Simulation results show that: the brittle cracking model based on Mode I fracture energy accurately simulates particle collision-induced fragmentation; particle fragmentation is primarily influenced by impact velocity; particles are more prone to fragmentation at higher incidence angles; fine particles are less likely to fragment, while larger particles may fragment even at low impact velocities.