Abstract: As modern mechanical engineering rapidly advances towards the nano realm, " Mechanical Analysis and Computation at Micro and Nano Scales " is increasingly becoming a significant interdisciplinary field in graduate training within mechanical engineering. This domain integrates multiple disciplines such as mechanical engineering, materials science, physics, chemistry, and computational science, offering abundant research and application opportunities for graduate students in mechanical engineering. The author explores incorporating " Mechanical Analysis and Computation at Micro and Nano Scales " into the graduate training programs of mechanical engineering within the context of the existing multidisciplinary framework of the department. By establishing an interdisciplinary talent cultivation model, reallocating high-quality course resources, and integrating experimental and practical training platforms, this approach aims to guide students in building a cross-disciplinary, cross-professional, and cross-domain knowledge system, thereby providing new perspectives for cultivating high-level, interdisciplinary talents for the new era.