Abstract: In this paper, the structural characteristic of open-press fuselage was first analyzed. Thenits mechanics model simplification method for thestructural analysis by finite element method was rec-ommended. Its finite eIement analysis and structureoptimization were made for open-press fuselage withseveral practical examples. A remarkable effect onreducing its weight and increasing its strength andrigidity was achieved. It provided a theoretical basefor reliable design and improvement of the structure.