Abstract: The mechanism of the bubble subsidence is studied based on hydrodynamics, focusing on the bubble subsidence behavior in vertically vibrating cylindrical vessels. With the consideration of additional mass and bubble compressibility, a mathematical model of the compressible bubble with subsidence effect is established, and the critical displacement and velocity of the bubble subsidence are obtained by the separating variable method. The results show that the amplitude and the frequency of the sinusoidal excitation are the important factors affecting the bubble subsidence, and they are closely related with the critical displacement and velocity, and the larger the amplitude and the frequency, the smaller the critical displacement, the easier the bubble sinks.